Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy.

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Melchiorre C, Bolognesi ML, Minarini A, Rosini M, Tumiatti V

Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy.

J Med Chem. 2010 Aug 26;53(16):5906-14. doi: 10.1021/jm100293f.

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20420456 [ View in PubMed

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Donepezil	Acetylcholinesterase	Ki (nM)	20.5	N/A	N/A	Details
Donepezil	Acetylcholinesterase	IC 50 (nM)	>100000	N/A	N/A	Details