The unexpected side effects of new nonsteroidal anti-inflammatory drugs.

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Uzan A

The unexpected side effects of new nonsteroidal anti-inflammatory drugs.

Expert Opin Emerg Drugs. 2005 Nov;10(4):687-8.

PubMed ID
16262557 [ View in PubMed
]
Abstract

Conventional nonselective NSAIDs are classically associated with a risk of gastrointestinal disorders. These drugs have a broad range of relative selectivity towards the COX family, mainly towards two isoforms of these enzymes: COX-1 and -2. As examples, ketorolac, flurbiprofen, ketoprofen and indomethacin have increased COX-1 selectivity when compared with naproxen and ibuprofen.

DrugBank Data that Cites this Article

Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
KetorolacProstaglandin G/H synthase 1ProteinHumans
Unknown
Inhibitor
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