Cloning and sequencing of a full length cDNA corresponding to human cellular retinol-binding protein.
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Colantuoni V, Cortese R, Nilsson M, Lundvall J, Bavik CO, Eriksson U, Peterson PA, Sundelin J
Cloning and sequencing of a full length cDNA corresponding to human cellular retinol-binding protein.
Biochem Biophys Res Commun. 1985 Jul 16;130(1):431-9.
- PubMed ID
- 2992469 [ View in PubMed]
- Abstract
We have isolated and sequenced a cDNA clone corresponding to the human cellular retinol-binding protein (CRBP). The deduced amino acid sequence, which encompasses 134 amino acid residues, shows significant homology with several low molecular weight proteins which bind hydrophobic ligands. No homology to the plasma retinol-binding protein was observed. Southern and Northern blot analyses suggest that the CRBP gene is present in a single copy in the haploid genome and that it is transcribed in a single mRNA species.