[Antiperspirants and deodorants--ingredients and evaluation].
Article Details
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Lukacs VA, Korting HC
[Antiperspirants and deodorants--ingredients and evaluation].
Derm Beruf Umwelt. 1989 Mar-Apr;37(2):53-7.
- PubMed ID
- 2656175 [ View in PubMed]
- Abstract
Antitranspirants and deodorants gain more and more interest. Aluminium chlorohydrate and aluminium zirkonium tetrachlorohydrate glycine complex are the most frequently used active ingredients in commercial antitranspirants today. Aluminium chloride and propantheline bromide, the anticholinergic substance, are important alternatives although less common. Active ingredients of deodorants are mainly perfumes or bactericidal/bacteriostatic substances, such as triclosan. In addition, there are substances which are meant to bind offending smells (e.g. zinc ricinoleate) or to influence the skin surface pH (e.g. triethyl citrate). As in the cosmetics industry in general, both safety and efficacy of a product are major parameters in the experimental and clinical evaluation. Establishment of efficacy is based on olfactory tests in model situations as well as on the detection of associated effects (e.g. influence on cutaneous microflora).
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Propantheline Muscarinic acetylcholine receptor M1 Protein Humans YesAntagonistDetails