Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline.

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Spiller H, Griffith J

Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline.

Clin Toxicol (Phila). 2008 Feb;46(2):171-2. doi: 10.1080/15563650701258070.

PubMed ID

18259967 [ View in PubMed

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Abstract

Tetrahydrozoline is an imidazoline derivative with alpha receptor agonist activity widely available in over-the-counter topical ocular and nasal formulations. More than 1,600 cases of oral exposures are reported to United States poison centers annually (1,2). Reports of significant toxicity from tetrahydrozoline ingestion are unusual but have occured primarily in small children after unintentional ingestion (3-63, 6). We report a case of unintentional tetrahydrozoline ingestion with cardiovascular effects persisting for 36 hours.

DrugBank Data that Cites this Article

Drugs

Tetryzoline

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Tetryzoline	Alpha-1 adrenergic receptors (Protein Group)	Protein group	Humans	Yes	Agonist	Details