Zinc, a structural component of adenylate kinases from gram-positive bacteria.

Article Details

Citation

Gilles AM, Glaser P, Perrier V, Meier A, Longin R, Sebald M, Maignan L, Pistotnik E, Barzu O

Zinc, a structural component of adenylate kinases from gram-positive bacteria.

J Bacteriol. 1994 Jan;176(2):520-3.

PubMed ID
8288548 [ View in PubMed
]
Abstract

The recent finding that Bacillus stearothermophilus adenylate kinase contains a zinc atom coordinated to four cysteines prompted us to investigate the metal-binding properties of the enzyme from various bacteria. We conclude that zinc was present only in adenylate kinase from gram-positive species and that this property is correlated with the presence of three or four Cys residues in the sequence Cys-X2-Cys-X16-Cys-X2-Cys/Asp, in which X stands for different amino acid residues.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Adenylate kinaseP84139Details