Structure of the DNA binding domain of E. coli SSB bound to ssDNA.
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Raghunathan S, Kozlov AG, Lohman TM, Waksman G
Structure of the DNA binding domain of E. coli SSB bound to ssDNA.
Nat Struct Biol. 2000 Aug;7(8):648-52.
- PubMed ID
- 10932248 [ View in PubMed]
- Abstract
The structure of the homotetrameric DNA binding domain of the single stranded DNA binding protein from Escherichia coli (Eco SSB) bound to two 35-mer single stranded DNAs was determined to a resolution of 2.8 A. This structure describes the vast network of interactions that results in the extensive wrapping of single stranded DNA around the SSB tetramer and suggests a structural basis for its various binding modes.