Coagulation factor V

BE0000041ProteinHumansF5

Central regulator of hemostasis. It is acted on by 10 drugs in DrugBank.

Gene name
F5
UniProtKB entry
P12259Swiss-Prot
Cellular location
Secreted
Residues / weight
2,224 residues · 251,701 Da
Also known as
Activated protein C cofactor · Proaccelerin, labile factor

Resolves to

Protein
UniProtP12259UniProt nameFA5_HUMAN
Gene
HGNCHGNC:3542NCBI Gene2153GenBank182412GeneCardsF5
Pharmacology
KEGGhsa:2153
Structure
PDB1CZSPDB1CZTPDB1CZV
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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56+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Coagulation factor V, how selective are they, and which programs against it are still in active trials?

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