| DB00055 | Drotrecogin alfa | approved, investigational, withdrawn | yes | multitarget | Details |
| DB05777 | Thrombomodulin Alfa | approved, investigational | unknown | | Details |
| DB09130 | Copper | approved, investigational | no | binder | Details |
| DB13149 | Protein S human | approved | yes | antagonist | Details |
| DB13151 | Anti-inhibitor coagulant complex | approved, investigational | yes | agonist | Details |
| DB13151 | Anti-inhibitor coagulant complex | approved, investigational | yes | substrate | Details |
| DB11572 | Thrombin alfa | approved | yes | activator | Details |
| DB11571 | Human thrombin | approved | yes | activator | Details |
| DB11300 | Thrombin | approved, investigational | yes | activator | Details |
| DB11312 | Protein C | approved | yes | inactivator | Details |