Neutral amino acid transporter B(0)

BE0000236ProteinHumansSLC1A5

Sodium-coupled antiporter of neutral amino acids. It is acted on by 4 drugs in DrugBank.

Gene name
SLC1A5
UniProtKB entry
Q15758Swiss-Prot
Cellular location
Cell membrane
Residues / weight
541 residues · 56,598 Da
Also known as
ASCT2 · ATB(0) · Baboon M7 virus receptor · M7V1 · RD114/simian type D retrovirus receptor

Resolves to

Protein
UniProtQ15758UniProt nameAAAT_HUMAN
Gene
HGNCHGNC:10943NCBI Gene6510GenBank1478281GeneCardsSLC1A5
Pharmacology
IUPHAR/GtoPdb874KEGGhsa:6510
Structure
PDB5LLMPDB5LLUPDB5LM4
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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37+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Neutral amino acid transporter B(0), how selective are they, and which programs against it are still in active trials?

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