Vasopressin V2 receptor

BE0000293ProteinHumansAVPR2

G protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption (PubMed:1534149, PubMed:19440390, PubMed:33664408, PubMed:33742150). It is acted on by 16 drugs in DrugBank.

Gene name
AVPR2
UniProtKB entry
P30518Swiss-Prot
Cellular location
Cell membrane
Residues / weight
371 residues · 40,279 Da
Also known as
ADHR · Antidiuretic hormone receptor · AVPR V2 · DIR · DIR3

Resolves to

Protein
UniProtP30518UniProt nameV2R_HUMAN
Gene
HGNCHGNC:897NCBI Gene554GenBank28418GeneCardsAVPR2
Pharmacology
IUPHAR/GtoPdb368KEGGhsa:554
Structure
PDB4JQIPDB6NI2PDB6U1N
Drugs

What you can answer from here — as of September 07, 2019

16DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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113+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Vasopressin V2 receptor, how selective are they, and which programs against it are still in active trials?

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