Melatonin receptor type 1B

BE0000327ProteinHumansMTNR1B

High affinity receptor for melatonin. It is acted on by 7 drugs in DrugBank.

Gene name
MTNR1B
UniProtKB entry
P49286Swiss-Prot
Cellular location
Cell membrane
Residues / weight
362 residues · 40,188 Da
Also known as
Mel-1B-R · Mel1b receptor

Resolves to

Protein
UniProtP49286UniProt nameMTR1B_HUMAN
Gene
HGNCHGNC:7464NCBI Gene4544GenBank971194GeneCardsMTNR1B
Pharmacology
IUPHAR/GtoPdb288KEGGhsa:4544
Structure
PDB6ME6PDB6ME7PDB6ME8
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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38+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Melatonin receptor type 1B, how selective are they, and which programs against it are still in active trials?

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