Taste receptor type 1 member 2

BE0000395ProteinHumansTAS1R2

Key component of the sweet taste receptor (PubMed:11917125, PubMed:40339580, PubMed:40754567, PubMed:40555359). It is acted on by 8 drugs in DrugBank.

Gene name
TAS1R2
UniProtKB entry
Q8TE23Swiss-Prot
Cellular location
Cell membrane
Residues / weight
839 residues · 95,183 Da
Also known as
G protein-coupled receptor 71 · GPR71 · Sweet taste receptor T1R2 · T1R2 · TR2

Resolves to

Protein
UniProtQ8TE23UniProt nameTS1R2_HUMAN
Gene
HGNCHGNC:14905NCBI Gene80834GenBank20142333GeneCardsTAS1R2
Pharmacology
KEGGhsa:80834
Structure
PDB9NORPDB9NOSPDB9NOT
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Taste receptor type 1 member 2, how selective are they, and which programs against it are still in active trials?

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