Prostacyclin receptor

BE0000475ProteinHumansPTGIR

Receptor for prostacyclin (prostaglandin I2 or PGI2). It is acted on by 18 drugs in DrugBank.

Gene name
PTGIR
UniProtKB entry
P43119Swiss-Prot
Cellular location
Cell membrane
Residues / weight
386 residues · 40,955 Da
Also known as
PGI receptor · PGI2 receptor · PRIPR · Prostaglandin I2 receptor · Prostanoid IP receptor

Resolves to

Protein
UniProtP43119UniProt namePI2R_HUMAN
Gene
HGNCHGNC:9602NCBI Gene5739GenBank495043GeneCardsPTGIR
Pharmacology
IUPHAR/GtoPdb345KEGGhsa:5739
Structure
PDB8X79PDB8X7A
Drugs

What you can answer from here — as of September 07, 2019

18DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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67+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Prostacyclin receptor, how selective are they, and which programs against it are still in active trials?

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