5-hydroxytryptamine receptor 1E

BE0000476ProteinHumansHTR1E

G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:14744596, PubMed:1513320, PubMed:1608964, PubMed:1733778, PubMed:21422162, PubMed:33762731). It is acted on by 13 drugs in DrugBank.

Gene name
HTR1E
UniProtKB entry
P28566Swiss-Prot
Cellular location
Cell membrane
Residues / weight
365 residues · 41,682 Da
Also known as
5-HT-1E · 5-HT1E · S31 · Serotonin receptor 1E

Resolves to

Protein
UniProtP28566UniProt name5HT1E_HUMAN
Gene
HGNCHGNC:5291NCBI Gene3354GenBank177774GeneCardsHTR1E
Pharmacology
IUPHAR/GtoPdb4KEGGhsa:3354
Structure
PDB7E33PDB8UGYPDB8UH3
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
11GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
35+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on 5-hydroxytryptamine receptor 1E, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In