Voltage-dependent T-type calcium channel subunit alpha-1G

BE0000483ProteinHumansCACNA1G

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell... It is acted on by 19 drugs in DrugBank.

Gene name
CACNA1G
UniProtKB entry
O43497Swiss-Prot
Cellular location
Membrane
Residues / weight
2,377 residues · 262,469 Da
Also known as
Cav3.1c · KIAA1123 · NBR13 · Voltage-gated calcium channel subunit alpha Cav3.1

Resolves to

Protein
UniProtO43497UniProt nameCAC1G_HUMAN
Gene
HGNCHGNC:1394NCBI Gene8913GenBank6625659
Pharmacology
IUPHAR/GtoPdb535KEGGhsa:8913
Drugs

What you can answer from here — as of September 07, 2019

19DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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58+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Voltage-dependent T-type calcium channel subunit alpha-1G, how selective are they, and which programs against it are still in active trials?

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