Interferon beta

BE0000926ProteinHumansIFNB1

Type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli (PubMed:10049744, PubMed:10556041, PubMed:6157094, PubMed:6171735, PubMed:7665574, PubMed:8027027, PubMed:8969169). It is acted on by 4 drugs in DrugBank.

Gene name
IFNB1
UniProtKB entry
P01574Swiss-Prot
Cellular location
Secreted
Residues / weight
187 residues · 22,294 Da
Also known as
Fibroblast interferon · IFB · IFN-beta · IFNB

Resolves to

Protein
UniProtP01574UniProt nameIFNB_HUMAN
Gene
HGNCHGNC:5434NCBI Gene3456GenBank32638GeneCardsIFNB1
Pharmacology
KEGGhsa:3456
Structure
PDB1AU1
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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27GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interferon beta, how selective are they, and which programs against it are still in active trials?

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