Low-density lipoprotein receptor-related protein 2

BE0000942ProteinHumansLRP2

Multiligand endocytic receptor (By similarity). It is acted on by 5 drugs in DrugBank.

Gene name
LRP2
UniProtKB entry
P98164Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
4,655 residues · 521,953 Da
Also known as
Glycoprotein 330 · gp330 · LRP-2 · Megalin

Resolves to

Protein
UniProtP98164UniProt nameLRP2_HUMAN
Gene
HGNCHGNC:6694NCBI Gene4036GenBank1809240GeneCardsLRP2
Pharmacology
KEGGhsa:4036
Structure
PDB2M0PPDB9CWMPDB9I3V
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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37GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Low-density lipoprotein receptor-related protein 2, how selective are they, and which programs against it are still in active trials?

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