Fibroblast growth factor 2

BE0001015ProteinHumansFGF2

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed:8663044). It is acted on by 14 drugs in DrugBank.

Gene name
FGF2
UniProtKB entry
P09038Swiss-Prot
Cellular location
Secreted
Residues / weight
288 residues · 30,770 Da
Also known as
Basic fibroblast growth factor · bFGF · FGF-2 · FGFB · HBGF-2

Resolves to

Protein
UniProtP09038UniProt nameFGF2_HUMAN
Gene
HGNCHGNC:3676NCBI Gene2247GenBank31362GeneCardsFGF2
Pharmacology
KEGGhsa:2247
Structure
PDB1BASPDB1BFBPDB1BFC
Drugs

What you can answer from here — as of September 07, 2019

14DrugsApproved to experimental, with action, bond type and pharmacological action
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47Clinical trialsTrials of drugs acting on it, by phase and status
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35GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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57+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fibroblast growth factor 2, how selective are they, and which programs against it are still in active trials?

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