Thymidine kinase, cytosolic

BE0001260ProteinHumansTK1

Cell-cycle-regulated enzyme of importance in nucleotide metabolism (PubMed:9575153). It is acted on by 27 drugs in DrugBank.

Gene name
TK1
UniProtKB entry
P04183Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
234 residues · 25,468 Da
Also known as
2.7.1.21

Resolves to

Protein
UniProtP04183UniProt nameKITH_HUMAN
Gene
HGNCHGNC:11830NCBI Gene7083GenBank339709GeneCardsTK1
Pharmacology
KEGGhsa:7083
Structure
PDB1W4RPDB1XBTPDB2ORV
Drugs

What you can answer from here — as of September 07, 2019

27DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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56+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thymidine kinase, cytosolic, how selective are they, and which programs against it are still in active trials?

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