Alovudine F-18

DB14930InvestigationalSmall molecule

Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography).

Chemical structure of Alovudine F-18
Mechanism
Curator reviewed
Formula / weight
C10H13FN2O4 · 243.225 g/mol (avg)
Also known as
18F-FLT · 3'-deoxy-3'- 18F fluorothymidine · 3'-Deoxy-3'-(18F) Fluorothymidine · 3'-deoxy-3'-[18F]fluorothymidine · 3'-Deoxy-3'-18F Fluorothymidine

Resolves to

Compound
UNII2X1K91UT6NCAS287114-80-1
Structure
InChIKeyUXCAQJAQSWSNPQ-ZIVQXEJRSA-NSMILESCC1=CN([C@H]2C[C@H]([18F])[C@@H](CO)O2)C(=O)NC1=O
Targets
P04183TK1
Transporters
Q99808SLC29A1Q14542SLC29A2

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
2TransportersSubstrate / inhibitor direction, not just membership
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14Drug interactionsStructured to mechanism, not free text
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22Clinical trialsPhase, status and sponsor resolved per trial
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5+ReferencesStructured and connected to the statements they support
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