Tubulin alpha-1B chain

BE0001275ProteinHumansTUBA1B

Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed:38305685, PubMed:34996871, PubMed:38609661). It is acted on by 5 drugs in DrugBank.

Gene name
TUBA1B
UniProtKB entry
P68363Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
451 residues · 50,151 Da
Also known as
3.6.5.- · Alpha-tubulin ubiquitous · Tubulin alpha-ubiquitous chain · Tubulin K-alpha-1

Resolves to

Protein
UniProtP68363UniProt nameTBA1B_HUMAN
Gene
HGNCHGNC:18809NCBI Gene10376GenBank340021GeneCardsTUBA1B
Pharmacology
KEGGhsa:10376
Structure
PDB2E4HPDB5IJ0PDB5IJ9
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tubulin alpha-1B chain, and which indications are they being tested in?

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