Hut operon positive regulatory protein

BE0001281ProteinBacillus subtilis (strain 168)hutP

Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization. It is acted on by 1 drug in DrugBank.

Gene name
hutP
UniProtKB entry
P10943Swiss-Prot
Residues / weight
148 residues · 16,195 Da

Resolves to

Protein
UniProtP10943UniProt nameHUTP_BACSU
Gene
NCBI Gene11241540GenBank143075
Structure
PDB1VEAPDB1WMQPDB1WPS
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
7+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Hut operon positive regulatory protein, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In