Amidophosphoribosyltransferase

BE0001375ProteinBacillus subtilis (strain 168)purF

Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. It is acted on by 1 drug in DrugBank.

Gene name
purF
UniProtKB entry
P00497Swiss-Prot
Residues / weight
476 residues · 51,691 Da
Also known as
2.4.2.14 · ATase · Glutamine phosphoribosylpyrophosphate amidotransferase · GPATase

Resolves to

Protein
UniProtP00497UniProt namePUR1_BACSU
Gene
NCBI Gene936046GenBank143369
Pharmacology
KEGGbsu:BSU06490
Structure
PDB1AO0PDB1GPH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Amidophosphoribosyltransferase, and which indications are they being tested in?

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