Hexitol phosphatase B

BE0001596ProteinEscherichia coli O157:H7hxpB

Sugar-phosphate phosphohydrolase that catalyzes the dephosphorylation of D-mannitol 1-phosphate and D-sorbitol 6-phosphate. It is acted on by 1 drug in DrugBank.

Gene name
hxpB
UniProtKB entry
Q7ADF8Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
222 residues · 24,329 Da
Also known as
2-deoxyglucose-6-phosphate phosphatase · 3.1.3.68 · Mannitol-1-phosphatase · Sorbitol-6-phosphatase · Sugar-phosphatase

Resolves to

Protein
UniProtQ7ADF8UniProt nameHXPB_ECO57
Gene
NCBI Gene912766GenBank12515740
Pharmacology
KEGGece:Z2756
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Hexitol phosphatase B, and which indications are they being tested in?

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