Glycerol-3-phosphate cytidylyltransferase

BE0001644ProteinBacillus subtilis (strain 168)tagD

Catalyzes the transfer of the cytidylyl group of CTP to sn-glycerol 3-phosphate so the activated glycerol 3-phosphate can be used for teichoic acid synthesis, via incorporation into both the linkage unit and the teichoic acid... It is acted on by 2 drugs in DrugBank.

Gene name
tagD
UniProtKB entry
P27623Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
129 residues · 15,271 Da
Also known as
2.7.7.39 · CDP-glycerol pyrophosphorylase · GCT · Teichoic acid biosynthesis protein D

Resolves to

Protein
UniProtP27623UniProt nameTAGD_BACSU
Gene
NCBI Gene936809GenBank143723
Pharmacology
KEGGbsu:BSU35740
Structure
PDB1COZPDB1N1D
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glycerol-3-phosphate cytidylyltransferase, and which indications are they being tested in?

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