Beta-lactamase Toho-1

BE0001755ProteinEscherichia colibla

Has strong cefotaxime-hydrolyzing activity. It is acted on by 7 drugs in DrugBank.

Gene name
bla
UniProtKB entry
Q47066Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
291 residues · 31,447 Da
Also known as
3.5.2.6

Resolves to

Protein
UniProtQ47066UniProt nameBLT1_ECOLX
Gene
GenBank1037162
Pharmacology
KEGGag:BAA07082
Structure
PDB1BZAPDB1IYOPDB1IYP
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Beta-lactamase Toho-1, how selective are they, and which programs against it are still in active trials?

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