DB00156ApprovedInvestigationalNutraceuticalSmall molecule
Threonine is an amino acid commonly found as a component of total parenteral nutrition. An essential amino acid occurring naturally in the L-form, which is the active form.
- Mechanism
- Curator reviewed
L-Threonine is a precursor to the amino acids glycine and serine. It acts as a lipotropic in controlling fat build-up in the liver. May help combat mental illness and may be very useful in indigestion and intestinal malfunctions. Also, threonine prevents excessive liver fat. Nutrients are more readily absorbed when threonine is present.
- Primary indication
- L-Threonine makes up collagen, elastin, and enamel protein.Curator reviewed · 1 structured indication
- Formula / weight
- C4H9NO3 · 119.1192 g/mol (avg)
- First approval
- Canada, 1997 · United States, 1971
- Also known as
- (2S)-threonine · L-Threonin · L-Threonine
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
AYFVYJQAPQTCCC-GBXIJSLDSA-NSMILESC[C@@H](O)[C@H](N)C(O)=OTransporters
What you can answer from here — as of September 23, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
1TransporterSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Threonine, and which of those have an active Phase 3 trial?
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