2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

BE0001839ProteinThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)ispD

Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). It is acted on by 1 drug in DrugBank.

Gene name
ispD
UniProtKB entry
Q9X1B3Swiss-Prot
Residues / weight
222 residues · 25,370 Da
Also known as
2.7.7.60 · 4-diphosphocytidyl-2C-methyl-D-erythritol synthase · MCT · MEP cytidylyltransferase

Resolves to

Protein
UniProtQ9X1B3UniProt nameISPD_THEMA
Gene
NCBI Gene898083GenBank4981955
Pharmacology
KEGGtma:TM1393
Structure
PDB1VPA
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In