Maltose/maltodextrin-binding periplasmic protein

BE0001996ProteinEscherichia coli (strain K12)malE

Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. It is acted on by 6 drugs in DrugBank.

Gene name
malE
UniProtKB entry
P0AEX9Swiss-Prot
Cellular location
Periplasm
Residues / weight
396 residues · 43,387 Da
Also known as
Maltodextrin-binding protein · Maltose-binding periplasmic protein · Maltose-binding protein · MBP · MMBP

Resolves to

Protein
UniProtP0AEX9UniProt nameMALE_ECOLI
Gene
NCBI Gene948538
Pharmacology
KEGGecj:JW3994
Structure
PDB1A7LPDB1ANFPDB1DMB
Drugs

What you can answer from here — as of May 03, 2025

6DrugsApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Maltose/maltodextrin-binding periplasmic protein, how selective are they, and which programs against it are still in active trials?

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