Bifunctional protein GlmU

BE0002025ProteinEscherichia coli (strain K12)glmU

Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). It is acted on by 3 drugs in DrugBank.

Gene name: glmU
UniProtKB entry: P0ACC7Swiss-Prot
Cellular location: Cytoplasm
Residues / weight: 456 residues · 49,190 Da
Also known as: yieA

Resolves to

Protein

UniProtP0ACC7UniProt nameGLMU_ECOLI

Gene

NCBI Gene948246

Pharmacology

KEGGecj:JW3708

Structure

PDB1FWYPDB1FXJPDB1HV9

Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action

12GO termsFunction, process and component, as structured annotations

2Pfam domainsDomain architecture mapped to Pfam families and clans

19+ReferencesStructured and connected to the statements they support

Which compounds in development act on Bifunctional protein GlmU, and which indications are they being tested in?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account