Low affinity immunoglobulin gamma Fc region receptor II-c

BE0002100ProteinHumansFCGR2C

Receptor for the Fc region of complexed immunoglobulins gamma. It is acted on by 5 drugs in DrugBank.

Gene name
FCGR2C
UniProtKB entry
P31995Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
323 residues · 35,578 Da
Also known as
CD32 · CDw32 · Fc-gamma RII-c · Fc-gamma-RIIc · FCG2

Resolves to

Protein
UniProtP31995UniProt nameFCG2C_HUMAN
Gene
HGNCHGNC:15626NCBI Gene9103GenBank32074GeneCardsFCGR2C
Pharmacology
KEGGhsa:9103
Structure
PDB3WJLPDB6YAX
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Low affinity immunoglobulin gamma Fc region receptor II-c, how selective are they, and which programs against it are still in active trials?

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