Methionyl-tRNA formyltransferase, mitochondrial

BE0002177ProteinHumansMTFMT

Methionyl-tRNA formyltransferase that formylates methionyl-tRNA in mitochondria and is crucial for translation initiation. It is acted on by 1 drug in DrugBank.

Gene name
MTFMT
UniProtKB entry
Q96DP5Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
389 residues · 43,832 Da
Also known as
2.1.2.9 · FMT · FMT1 · MtFMT

Resolves to

Protein
UniProtQ96DP5UniProt nameFMT_HUMAN
Gene
HGNCHGNC:29666NCBI Gene123263GenBank133777035GeneCardsMTFMT
Pharmacology
KEGGhsa:123263
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Methionyl-tRNA formyltransferase, mitochondrial, and which indications are they being tested in?

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