Granulocyte-macrophage colony-stimulating factor

BE0002481ProteinHumansCSF2

Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. It is acted on by 11 drugs in DrugBank.

Gene name
CSF2
UniProtKB entry
P04141Swiss-Prot
Cellular location
Secreted
Residues / weight
144 residues · 16,295 Da
Also known as
Colony-stimulating factor · CSF · GM-CSF · GMCSF · Molgramostin

Resolves to

Protein
UniProtP04141UniProt nameCSF2_HUMAN
Gene
HGNCHGNC:2434NCBI Gene1437GeneCardsCSF2
Pharmacology
KEGGhsa:1437
Structure
PDB1CSGPDB2GMFPDB4NKQ
Drugs

What you can answer from here — as of September 07, 2019

11DrugsApproved to experimental, with action, bond type and pharmacological action
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25Clinical trialsTrials of drugs acting on it, by phase and status
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19GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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35+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Granulocyte-macrophage colony-stimulating factor, how selective are they, and which programs against it are still in active trials?

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