Endoribonuclease EndoA

BE0002696ProteinBacillus subtilis (strain 168)ndoA

Toxic component of a type II toxin-antitoxin (TA) system. It is acted on by 1 drug in DrugBank.

Gene name
ndoA
UniProtKB entry
P96622Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
116 residues · 12,978 Da
Also known as
3.1.27.- · mazF · MazF-bs · mRNA interferase EndoA · mRNA interferase MazF-bs

Resolves to

Protein
UniProtP96622UniProt nameENDOA_BACSU
Gene
NCBI Gene939935
Pharmacology
KEGGbsu:BSU04660
Structure
PDB1NE8PDB4MDXPDB4ME7
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Endoribonuclease EndoA, and which indications are they being tested in?

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