Adenine DNA glycosylase

BE0002755ProteinEscherichia coli (strain K12)mutY

Adenine glycosylase active on G-A mispairs. It is acted on by 5 drugs in DrugBank.

Gene name
mutY
UniProtKB entry
P17802Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
350 residues · 39,149 Da
Also known as
3.2.2.- · 3.2.2.31 · A/G-specific adenine glycosylase · micA

Resolves to

Protein
UniProtP17802UniProt nameMUTY_ECOLI
Gene
NCBI Gene947447
Pharmacology
KEGGecj:JW2928
Structure
PDB1KG2PDB1KG3PDB1KG4
Drugs

What you can answer from here — as of September 04, 2024

5DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Adenine DNA glycosylase, how selective are they, and which programs against it are still in active trials?

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