Free fatty acid receptor 4

BE0003399ProteinHumansFFAR4

G protein-coupled receptor for long-chain fatty acids (LCFAs) with a major role in adipogenesis, energy metabolism and inflammation. It is acted on by 4 drugs in DrugBank.

Gene name
FFAR4
UniProtKB entry
Q5NUL3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
361 residues · 40,494 Da
Also known as
G protein-coupled receptor 120 · G protein-coupled receptor 129 · G protein-coupled receptor GT01 · G protein-coupled receptor PGR4 · GPR120

Resolves to

Protein
UniProtQ5NUL3UniProt nameFFAR4_HUMAN
Gene
HGNCHGNC:19061NCBI Gene338557GeneCardsFFAR4
Pharmacology
IUPHAR/GtoPdb127KEGGhsa:338557
Structure
PDB8G59PDB8H4IPDB8H4K
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Free fatty acid receptor 4, how selective are they, and which programs against it are still in active trials?

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