Genome polyprotein

BE0003427Protein

Mature core protein Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). It is acted on by 39 drugs in DrugBank.

UniProtKB entry
P26664Swiss-Prot
Cellular location
Host endoplasmic reticulum membrane
Residues / weight
3,011 residues · 327,199 Da
Also known as
3.4.22.- · p23

Resolves to

Protein
UniProtP26664UniProt namePOLG_HCV1
Structure
PDB1RTLPDB2A4GPDB2GVF
Drugs

What you can answer from here — as of September 07, 2019

39DrugsApproved to experimental, with action, bond type and pharmacological action
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37GO termsFunction, process and component, as structured annotations
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15Pfam domainsDomain architecture mapped to Pfam families and clans
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56+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Genome polyprotein, how selective are they, and which programs against it are still in active trials?

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