Calpain-3

BE0003470ProteinHumansCAPN3

Calcium-regulated non-lysosomal thiol-protease. It is acted on by 1 drug in DrugBank.

Gene name
CAPN3
UniProtKB entry
P20807Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
821 residues · 94,253 Da
Also known as
3.4.22.54 · Calcium-activated neutral proteinase 3 · Calpain L3 · Calpain p94 · CANP 3

Resolves to

Protein
UniProtP20807UniProt nameCAN3_HUMAN
Gene
HGNCHGNC:1480NCBI Gene825GeneCardsCAPN3
Pharmacology
KEGGhsa:825
Structure
PDB4OKHPDB6BDTPDB6BGP
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Calpain-3, and which indications are they being tested in?

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