Lymphocyte antigen 96

BE0004024ProteinHumansLY96

Binds bacterial lipopolysaccharide (LPS) (PubMed:17569869, PubMed:17803912). It is acted on by 6 drugs in DrugBank.

Gene name
LY96
UniProtKB entry
Q9Y6Y9Swiss-Prot
Cellular location
Secreted, extracellular space
Residues / weight
160 residues · 18,545 Da
Also known as
ESOP-1 · ESOP1 · Ly-96 · MD2 · Protein MD-2

Resolves to

Protein
UniProtQ9Y6Y9UniProt nameLY96_HUMAN
Gene
HGNCHGNC:17156NCBI Gene23643GenBank5051740GeneCardsLY96
Pharmacology
IUPHAR/GtoPdb2890KEGGhsa:23643
Structure
PDB2E56PDB2E59PDB2Z65
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Lymphocyte antigen 96, how selective are they, and which programs against it are still in active trials?

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