This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Cobalt is a metal element used in various nutritional products.

Generic Name
Cobalt
DrugBank Accession Number
DB14574
Background

A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. Except for radioactive forms of cobalt and cobalamin, the FDA withdrew its approval for the use of drug products containing cobalt salts.1

Type
Small Molecule
Groups
Approved, Experimental, Withdrawn
Structure
Weight
Average: 58.9332
Monoisotopic: 58.933200194
Chemical Formula
Co
Synonyms
  • Cobalt
  • Cobalt, elemental
  • Cobalto
  • Cobaltum
  • Kobalt

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Oligofer LiqCobalt (.64 mg / mL) + Cyanocobalamin (2.5 mcg / mL) + Ferrous gluconate (2 mg / mL) + Manganese (.2 mg / mL)LiquidOralSabex Inc1993-12-311999-08-12Canada flag
Oligostim Manganese-cobaltCobalt (0.029 mg) + Manganese (0.027 mg)TabletOralDolisos Laboratoires S.A.1998-04-032007-08-01Canada flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
3G0H8C9362
CAS number
7440-48-4
InChI Key
GUTLYIVDDKVIGB-UHFFFAOYSA-N
InChI
InChI=1S/Co
IUPAC Name
cobalt
SMILES
[Co]

References

General References
  1. Code of Federal Regulations 216.24: Drug products withdrawn or removed from the market for reasons of safety or effectiveness. [Link]
KEGG Compound
C19171
ChemSpider
94547
RxNav
1310300
ChEBI
27638
PDBe Ligand
3CO
Wikipedia
Cobalt

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LiquidSublingual29.5 mcg / mL
LiquidOral
TabletOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0 mg/mLALOGPS
logP-1.3ALOGPS
logP0.23Chemaxon
logS1.08ALOGPS
Physiological Charge0Chemaxon
Hydrogen Acceptor Count0Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity0 m3·mol-1Chemaxon
Polarizability1.78 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created at July 20, 2018 21:22 / Updated at December 01, 2022 11:28