Bifunctional protein GlmU

BE0004280ProteinHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)glmU

Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). It is acted on by 1 drug in DrugBank.

Gene name
glmU
UniProtKB entry
P43889Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
456 residues · 49,287 Da
Also known as
2.7.7.23

Resolves to

Protein
UniProtP43889UniProt nameGLMU_HAEIN
Gene
NCBI Gene949691GenBank3212176
Pharmacology
KEGGhin:HI0642
Structure
PDB2V0HPDB2V0IPDB2V0J
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Bifunctional protein GlmU, and which indications are they being tested in?

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