Lipase EstA

BE0004332ProteinBacillus subtilis (strain 168)estA

Active toward triacylglycerides with a preference for esters with C8:0 acyl groups; barely active on C18:1 or C18:4 substrates. It is acted on by 2 drugs in DrugBank.

Gene name
estA
UniProtKB entry
P37957Swiss-Prot
Cellular location
Secreted
Residues / weight
212 residues · 22,791 Da
Also known as
lip · lipA · Lipase A · Triacylglycerol lipase

Resolves to

Protein
UniProtP37957UniProt nameESTA_BACSU
Gene
NCBI Gene938389GenBank143154
Pharmacology
KEGGbsu:BSU02700
Structure
PDB1I6WPDB1ISPPDB1R4Z
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Lipase EstA, and which indications are they being tested in?

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