Calcium-activated potassium channel subunit beta-4

BE0004424ProteinHumansKCNMB4

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. It is acted on by 2 drugs in DrugBank.

Gene name
KCNMB4
UniProtKB entry
Q86W47Swiss-Prot
Cellular location
Membrane
Residues / weight
210 residues · 23,948 Da
Also known as
BK channel subunit beta-4 · BKbeta4 · Calcium-activated potassium channel, subfamily M subunit beta-4 · Charybdotoxin receptor subunit beta-4 · Hbeta4

Resolves to

Protein
UniProtQ86W47UniProt nameKCMB4_HUMAN
Gene
HGNCHGNC:6289NCBI Gene27345GenBank7799988GeneCardsKCNMB4
Pharmacology
KEGGhsa:27345
Structure
PDB5Y7LPDB6V22PDB6V35
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Calcium-activated potassium channel subunit beta-4, and which indications are they being tested in?

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