Mannose-binding protein C

BE0004482ProteinHumansMBL2

Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the... It is acted on by 9 drugs in DrugBank.

Gene name
MBL2
UniProtKB entry
P11226Swiss-Prot
Cellular location
Secreted
Residues / weight
248 residues · 26,143 Da
Also known as
COLEC1 · Collectin-1 · Mannan-binding protein · Mannose-binding lectin · MBL

Resolves to

Protein
UniProtP11226UniProt nameMBL2_HUMAN
Gene
HGNCHGNC:6922NCBI Gene4153GeneCardsMBL2
Pharmacology
KEGGhsa:4153
Structure
PDB1HUP
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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32+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Mannose-binding protein C, and which indications are they being tested in?

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