Serine/threonine-protein kinase SIK1

BE0004757ProteinHumansSIK1

Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. It is acted on by 2 drugs in DrugBank.

Gene name
SIK1
UniProtKB entry
P57059Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
783 residues · 84,901 Da
Also known as
2.7.11.1 · Salt-inducible kinase 1 · Serine/threonine-protein kinase SNF1-like kinase 1 · Serine/threonine-protein kinase SNF1LK · SIK

Resolves to

Protein
UniProtP57059UniProt nameSIK1_HUMAN
Gene
HGNCHGNC:11142NCBI Gene150094GeneCardsSIK1
Pharmacology
IUPHAR/GtoPdb2197KEGGhsa:150094
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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21GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serine/threonine-protein kinase SIK1, how selective are they, and which programs against it are still in active trials?

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