Metallothionein-1A

BE0004778ProteinHumansMT1A

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. It is acted on by 8 drugs in DrugBank.

Gene name
MT1A
UniProtKB entry
P04731Swiss-Prot
Residues / weight
61 residues · 6,120 Da
Also known as
Metallothionein-IA · MT-1A · MT-IA · MT1S

Resolves to

Protein
UniProtP04731UniProt nameMT1A_HUMAN
Gene
HGNCHGNC:7393NCBI Gene4489GeneCardsMT1A
Pharmacology
KEGGhsa:4489
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Metallothionein-1A, how selective are they, and which programs against it are still in active trials?

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