Sodium-dependent phosphate transport protein 2A

BE0008681ProteinHumansSLC34A1

Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (PubMed:12324554, PubMed:20335586, PubMed:26047794, PubMed:8327470). It is acted on by 5 drugs in DrugBank.

Gene name
SLC34A1
UniProtKB entry
Q06495Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
639 residues · 68,937 Da
Also known as
Na(+)-dependent phosphate cotransporter 2A · Na(+)/Pi cotransporter 2A · NaPi-2a · NaPi-3 · NPT2

Resolves to

Protein
UniProtQ06495UniProt nameNPT2A_HUMAN
Gene
HGNCHGNC:11019NCBI Gene6569GeneCardsSLC34A1
Pharmacology
KEGGhsa:6569
Drugs

What you can answer from here — as of September 03, 2024

5DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium-dependent phosphate transport protein 2A, how selective are they, and which programs against it are still in active trials?

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