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Sodium phosphate, dibasic is an osmotic laxative used to cleanse the colon before a colonoscopy.
- Mechanism
- Curator reviewed · 1 reference
Sodium phosphate is thought to work by increasing the amount of solute present in the intestinal lumen thereby creating an osmotic gradient which draws water into the lumen.
- Primary indication
- Used to treat constipation or to clean the bowel before a colonoscopy.Curator reviewed · 6 structured indications
- Formula / weight
- HNa2O4P · 141.9588 g/mol (avg)
- First approval
- Canada, 1996 · United States, 1981
- Also known as
- Disodium acid phosphate · Disodium hydrogen monophosphate · Disodium hydrogen phosphate · disodium hydrogenphosphate · Disodium phosphate
- Code names
- E-339(II) · Fema no. 2398 · INS-339(II) · INS NO.339(II)
- Brand names
- Bss Ophthalmic Solution
- Fleet Mineral Oil
- Glycerolyte 57
- Isolyte S pH 7.4
- K-phos Neutral
- Osmoprep
- Pedia-lax Liquid
- Tis-U-sol
Resolves to
Clinical / RWD
Structure
InChIKey
BNIILDVGGAEEIG-UHFFFAOYSA-LSMILES[Na+].[Na+].OP([O-])([O-])=OTargets
What you can answer from here — as of September 23, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
5TransportersSubstrate / inhibitor direction, not just membership
Listed above
Which drugs share a target with Sodium phosphate, dibasic, and which of those have an active Phase 3 trial?