Sodium-dependent phosphate transport protein 2B

BE0008682ProteinHumansSLC34A2

Involved in actively transporting phosphate into cells via Na(+) cotransport. It is acted on by 7 drugs in DrugBank.

Gene name
SLC34A2
UniProtKB entry
O95436Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
690 residues · 75,759 Da
Also known as
Na(+)-dependent phosphate cotransporter 2B · Na(+)/Pi cotransporter 2B · NaPi-2b · NaPi3b · Sodium-phosphate transport protein 2B

Resolves to

Protein
UniProtO95436UniProt nameNPT2B_HUMAN
Gene
HGNCHGNC:11020NCBI Gene10568GeneCardsSLC34A2
Pharmacology
IUPHAR/GtoPdb1136KEGGhsa:10568
Drugs

What you can answer from here — as of September 03, 2024

7DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium-dependent phosphate transport protein 2B, how selective are they, and which programs against it are still in active trials?

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