Sodium-dependent phosphate transport protein 2C

BE0008683ProteinHumansSLC34A3

Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (PubMed:11880379). It is acted on by 5 drugs in DrugBank.

Gene name
SLC34A3
UniProtKB entry
Q8N130Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
599 residues · 63,549 Da
Also known as
Na(+)-dependent phosphate cotransporter 2C · Na(+)/Pi cotransporter 2C · NaPi-2c · NPT2C · NPTIIC

Resolves to

Protein
UniProtQ8N130UniProt nameNPT2C_HUMAN
Gene
HGNCHGNC:20305NCBI Gene142680GeneCardsSLC34A3
Pharmacology
KEGGhsa:142680
Drugs

What you can answer from here — as of September 03, 2024

5DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium-dependent phosphate transport protein 2C, how selective are they, and which programs against it are still in active trials?

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